COVID-19 Vaccine Storage Tembiricha: Nei iyo ULT Freezer?

Musi waZvita 8, United Kingdom yakava nyika yekutanga pasirese kutanga kubaya vagari vemo nePfizer's yakatenderwa zvizere uye yakavhenekwa COVID-19 vaccine.Musi waZvita 10, The Food and Drug Administration (FDA) ichasangana kuti ikurukure mvumo yekukurumidzira yejekiseni rimwe chete.Munguva pfupi iri kutevera, nyika pasi rese dzichange dzichiteverawo, dzichitora matanho chaiwo ekuendesa zvakachengeteka mamiriyoni emabhodhoro egirazi kuruzhinji.

Kuchengeta tembiricha inodiwa yepasi-zero inodiwa kuchengetedza kuvimbika kwejekiseni ichave chinhu chikuru kune vanogovera vaccine.Zvino, kana majekiseni akamirirwa kwenguva refu asvika kuma pharmacy nezvipatara, anofanirwa kuramba achichengetwa pazasi-zero tembiricha.

Sei COVID-19 Vaccines Inoda Ultra-yakaderera Tembiricha?

Kusiyana nejekiseni refuruwenza, iro rinoda kuchengetwa pa5 degrees Celsius, Pfizer's COVID-19 vaccine inoda kuchengetwa pa -70 degrees Celsius.Iyi tembiricha yepasi-zero inongodziya ingangoita 30 madhigirii kupfuura tembiricha inotonhora zvakanyanya yakanyorwa muAntarctica.Kunyangwe isinganyanyi kutonhora, yekudzivirira yeModerna ichiri kuda pasi pe zero tembiricha ye -20 madhigirii Celsius, kuitira kuchengetedza simba rayo.

Kuti tinzwisise zvizere kudiwa kwekutonhora kwechando, ngationgororei zvikamu zvejekiseni uye kuti majekiseni ekudzivirira aya anoshanda chaizvo.

mRNA Technology

Majekiseni ekudzivirira, senge furuwenza yemwaka, kusvika parizvino ashandisa hutachiona husina simba kana husina kusimba kukurudzira mhinduro yezvirwere mumuviri.Iwo ekudzivirira eCCIDID-19 anogadzirwa naPfizer uye Moderna anoshandisa mutumwa RNA, kana mRNA kwenguva pfupi.mRNA inoshandura maseru emunhu kuita mafekitori, achivagonesa kugadzira chaiyo coronavirus protein.Protein inogadzira mhinduro yekudzivirira mumuviri, sekunge paine hutachiona hwekoronavirus chaiyo.Mune ramangwana, kana munhu akafumurwa coronavirus, immune system inogona kurwisa zviri nyore.

mRNA vaccine tekinoroji inyowani kwazvo uye iyo COVID-19 yekudzivirira ichave yekutanga yerudzi rwayo kubvumidzwa neFDA.

Iyo Fragility ye mRNA

Iyo mRNA molecule haina kusimba zvakanyanya.Hazvitore zvakawanda kuita kuti iparare.Kuratidzira kune tembiricha isingachinjiki kana ma enzymes anogona kukuvadza molekuru.Kuchengetedza vaccine kubva kuma enzymes mumuviri wedu, Pfizer yakaputira iyo mRNA mumabhuru ane mafuta akagadzirwa nelipid nanoparticles.Kunyangwe nebubble rekudzivirira, iyo mRNA inogona kuramba ichidzikisira nekukurumidza.Kuchengeta vaccine pazasi-zero tembiricha kunodzivirira kuparara uku, kuchengetedza kuvimbika kwejekiseni.

Sarudzo nhatu dzeCOVID-19 Vaccine Storage

Sekureva kwaPfizer, vagoveri vekudzivirira vane sarudzo nhatu kana zvasvika pakuchengeta yavo COVID-19 vaccine.Vashambadziri vanogona kushandisa mafiriza eULT, shandisa vatakuri vemafuta kuti vachengete kwenguva pfupi kusvika mazuva makumi matatu (vanofanira kuzadza neaizi yakaoma mazuva mashanu ega ega), kana kuchengeta mufiriji yekudzivirira kwemazuva mashanu.Mugadziri wemishonga akaisa vafambisi vezvikepe zvinopisa vachishandisa aizi yakaoma uye GPS-inogonesa thermal sensors kudzivirira mafambiro etembiricha vari munzira kuenda kunzvimbo yekushandisa (POU).