Covid-19 Vaccine Storage

Chii chinonzi Covid-19 Vaccine?
Iyo Covid - 19 yekudzivirira, inotengeswa pasi pezita rechiratidzo Comirnaty, ndeye mRNA-yakavakirwa Covid - 19 yekudzivirira.Yakagadzirirwa kuongororwa kwekliniki uye kugadzira.Jekiseni rinopihwa nejekiseni remukati memuscular, richida kuti madhodhi maviri apihwe masvondo matatu akaparadzana.Ndiyo imwe yemishonga miviri yeRNA yakaiswa kurwisa Covid-19 muna 2020, imwe yacho iri yeModerna vaccine.

Mushonga uyu waive wekutanga COVID - 19 vaccine kupihwa mvumo nechiremera chekushandisa nekukurumidza uye yekutanga kucheneswa kushandiswa nguva dzose.Muna Zvita 2020, United Kingdom ndiyo yaive nyika yekutanga kupa mvumo yekudzivirira pachiitiko chekukurumidzira, ichiteverwa neUnited States, European Union nedzimwe nyika dzakawanda pasi rose.Pasi rose, makambani ane chinangwa chekugadzira mishonga inosvika mabhiriyoni maviri nemazana mashanu emadhora muna 2021. Zvakadaro, kugovera nekuchengetwa kwejekiseni idambudziko rekugadzirisa zvinhu nekuti rinoda kuchengetedzwa pakadzikira zvakanyanya.

Ndezvipi zvinosanganiswa muCovid-19 Vaccine?
Iyo Pfizer BioNTech Covid-19 yekudzivirira ndeyemutumwa RNA (mRNA) yekudzivirira iyo ine zvese synthetic, kana makemikari akagadzirwa, zvikamu uye enzymatic inogadzirwa zvinhu kubva kune zvinongoitika zvinhu zvakaita semapuroteni.Mushonga wekudzivirira hauna chero hutachiona hwehupenyu.Zvinhu zvaro zvisingashande zvinosanganisira potassium chloride, monobasic potassium, phosphate, sodium chloride, dibasic sodium phosphate dihydrate, uye sucrose, pamwe chete nezvimwe zvidiki zvezvimwe zvinhu.

Kuchengetedzwa kweCovid-19 Vaccine
Parizvino, jekiseni rinofanirwa kuchengetwa mufiriza ine ultra-low pane tembiricha iri pakati pe -80ºC kusvika -60ºC, umo rinogona kuchengetwa kwemwedzi mitanhatu.Inogona zvakare kuiswa mufiriji kwemazuva anosvika mashanu pane yakajairika tembiricha yefiriji (pakati pe + 2⁰C uye + 8⁰C) isati yasanganiswa nesaline diluent.

Inotumirwa mumudziyo wakanyatsogadzirwa wekutakura unogona kushandiswawo sekuchengetedza kwenguva pfupi kusvika kumazuva makumi matatu.

Nekudaro, Pfizer neBioNTech vachangobva kuendesa data nyowani kuUS Food and Drug Administration (FDA) inoratidza kugadzikana kwemushonga wavo weCovid-19 patembiricha inodziya.Iyo data nyowani inoratidza kuti inogona kuchengetwa pakati -25 ° C kusvika -15 ° C, tembiricha inowanzowanikwa mumafiriza emishonga uye mafiriji.

Zvichitevera iyi data, EU neFDA muUSA dzakatendera aya mamiriro matsva ekuchengetera achibvumira kuti jekiseni richengetedzwe patembiricha yefiriza yemishonga kwemavhiki maviri.

Iyi gadziriso kune zvazvino zvekuchengetera zvinodiwa zvekudzivirira kwePfizer zvinogadzirisa zvimwe zvipimo pakuisa kwejab uye zvinogona kubvumira kubuda kwejekiseni kuri nyore munyika dzisina zvivakwa zvekutsigira tembiricha yakaderera-yakaderera, zvichiita kuti kugovera kuve kushoma. kunetseka.

Nei tembiricha yekuchengetedza yeCovid-19 ichitonhora kudaro?
Chikonzero nei mushonga weCovid-19 uchifanira kuchengetwa uchitonhora nekuda kwemRNA mukati.Kushandisa mRNA tekinoroji kwave kwakakosha mukugadzira yakachengeteka, inoshanda yekudzivirira nekukurumidza, asi mRNA pachayo haina kusimba zvakanyanya sezvo inopunzika nekukurumidza uye nyore.Kusagadzikana uku ndiko kwaita kuti kugadzira mRNA-based vaccine kunetsa munguva yakapfuura.

Neraki, basa rakawanda rapinda mukugadzira nzira uye tekinoroji inoita kuti mRNA igadzikane, saka inogona kubudirira kuiswa mujekiseni.Nekudaro, yekutanga Covid-19 mRNA yekudzivirira icharamba ichida kutonhora kuchengetwa kunosvika 80ºC kuona kuti mRNA iri mukati memushonga inoramba yakagadzikana, iyo inotonhora zvakanyanya kupfuura iyo yakajairwa firiza.Idzi tembiricha dzinotonhora zvakanyanya dzinongodiwa chete kuchengetedza sezvo jekiseni rinonyungudutswa risati rabaya jekiseni.

Carebios 'Zvigadzirwa zvekuchengetera Vaccine
Carebios 'yakanyanya-yakaderera tembiricha mafiriza anopa mhinduro yekunyanya kudzika tembiricha yekuchengetedza, iyo yakanakira yekudzivirira yeCovid-19.Mafiriza edu ekupedzisira-akaderera tembiricha, anozivikanwawo semafiriji eULT, anowanzo kuve nemhando yetembiricha ye -45 ° C kusvika -86 ° C uye anoshandiswa kuchengetedza mishonga, ma enzymes, makemikari, mabhakitiriya uye mamwe masampuli.

Yedu yakaderera tembiricha mafiriza anowanikwa mune akasiyana dhizaini uye saizi zvichienderana nekuti yakawanda sei yekuchengetedza inodiwa.Panowanzove neshanduro mbiri, firiza yakamira kana firiza yechipfuva ine mukana kubva kumusoro.Iyo yemukati yekuchengetera vhoriyamu inogona kazhinji kutanga kubva mukati mehuwandu hwe128 litres kusvika pahurefu hwehuwandu hwe730 litres.Iyo inowanzo ine masherufu mukati umo maesamples ekutsvagisa anoiswa uye sherefu yega yega inovharwa nemusuwo wemukati kuitira kuchengetedza tembiricha seyakafanana sezvinobvira.

Yedu -86 ° C mhando yeakanyanya-yakaderera tembiricha mafiriza anovimbisa kuchengetedzwa kwakanyanya kwemasamples nguva dzese.Kuchengetedza sampuli, mushandisi uye nharaunda, mafiriza edu etembiricha akadzikira anogadzirwa kusvika kune dzimwe nyika izvo zvinoreva kushanda kwesimba kukuchengetedza mari uye kubatsira kuchengetedza kuburitsa kwezvakatipoteredza kwakaderera.

Nekukosha kusingakundiki kwemari, tembiricha yedu yakaderera yefiriza yakanakira kuchengetedza kwenguva refu sampuli.Mavhoriyamu akatsanangurwa anotangira pa128 kusvika pa730L.

Iwo ekupedzisira akaderera mafiriza akagadzirirwa kuchengetedzwa kwakanyanya nekuda kweiyo yakasimba dhizaini, inopa kugadzirisa kuri nyore uye inoenderana nemitsva yeF-Gasi mirau yezvakatipoteredza.

Bata Bata Kuti uwane rumwe Ruzivo
Kuti uzive zvakawanda nezve yakaderera tembiricha mafiriza atinopa kuCarebios kana kubvunza nezve Ultra yakaderera tembiricha firiza yekuchengetera yekudzivirira yeCovid-19, ndapota usazeza kubata nenhengo yechikwata chedu nhasi.